Journal: RSC Advances

Article Title: Mononuclear Mg( ii ) and Ca( ii ) metallocarboxylates of N -phthaloyl- γ -aminobutyric acid: synthesis, characterization, ds-DNA binding, preliminary anticancer evaluation against MDA-MB-231 cells, and computational studies

doi: 10.1039/d6ra07684j

Figure Lengend Snippet: Anticancer activity of NY0, NY1 and NY2 against triple-negative MDA-MB-231 breast cancer cell lines: (a) cytotoxic effect against MDA-MB-231 cell lines and (b) viability against normal skin HaCaT cells.

Article Snippet: The triple-negative breast cancer (TNBC) cell line MDA-MB-231 (ATCC HTB-26) and the normal human breast epithelial cell line MCF-10A (ATCC CRL-10317) used in this study were purchased from the American Type Culture Collection (ATCC), USA.

Techniques: Activity Assay

Journal: RSC Advances

Article Title: Mononuclear Mg( ii ) and Ca( ii ) metallocarboxylates of N -phthaloyl- γ -aminobutyric acid: synthesis, characterization, ds-DNA binding, preliminary anticancer evaluation against MDA-MB-231 cells, and computational studies

doi: 10.1039/d6ra07684j

Figure Lengend Snippet: IC 50 values for the treated MDA-MB-231 cancer and MCF-10A normal cells

Article Snippet: The triple-negative breast cancer (TNBC) cell line MDA-MB-231 (ATCC HTB-26) and the normal human breast epithelial cell line MCF-10A (ATCC CRL-10317) used in this study were purchased from the American Type Culture Collection (ATCC), USA.

Techniques:

Journal: Frontiers in Public Health

Article Title: Evaluation of the radiomodifying effects of Ginkgo biloba in radioresistant triple negative breast cancer cells

doi: 10.3389/fpubh.2026.1952136

Figure Lengend Snippet: Concentration- and time dependent effects of Ginkgo biloba (GB) treatment, alone and in combination with 3 Gy irradiation, on the viability of MDA-MB-231 cells as determined by MTT assay. Cell viability was assessed at 24 h (A) , 48 h (B) and 72 h (C) following treatment with increasing concentrations of GB. Data are presented as mean ± SD from three independent biological experiments. Asterisks indicate significant differences compared with the corresponding untreated control (0 μg/mL GB): p < 0.05 (*) and p < 0.01 (**).

Article Snippet: The human triple-negative breast cancer (TNBC) parental cell line MDA-MB-231 (HTB-26, ATCC, Manassas, VA, USA) was cultured in DMEM supplemented with 10% heat-inactivated FBS and 1% penicillin–streptomycin.

Techniques: Concentration Assay, Irradiation, MTT Assay, Control

Journal: Frontiers in Public Health

Article Title: Evaluation of the radiomodifying effects of Ginkgo biloba in radioresistant triple negative breast cancer cells

doi: 10.3389/fpubh.2026.1952136

Figure Lengend Snippet: Effects of Ginkgo biloba (GB) treatment, alone and in combination with 3 Gy irradiation, on intracellular reactive oxygen species (ROS) generation in MDA-MB-231 cells, assessed by flow cytometry using CellROX ® Green staining. Cells treated with TBHP (positive control) and untreated cells (negative control) are shown in panel (A) . Cells were treated with increasing concentrations of GB (0–300 μg/mL), and the percentage of live cells (B) and intracellular ROS levels (C) were evaluated in non-irradiated and irradiated groups. Data are presented as mean ± SD from three independent biological experiments.

Article Snippet: The human triple-negative breast cancer (TNBC) parental cell line MDA-MB-231 (HTB-26, ATCC, Manassas, VA, USA) was cultured in DMEM supplemented with 10% heat-inactivated FBS and 1% penicillin–streptomycin.

Techniques: Irradiation, Flow Cytometry, Staining, Positive Control, Negative Control

Journal: Frontiers in Public Health

Article Title: Evaluation of the radiomodifying effects of Ginkgo biloba in radioresistant triple negative breast cancer cells

doi: 10.3389/fpubh.2026.1952136

Figure Lengend Snippet: Effects of Ginkgo biloba (GB) treatment on the percentage of live MDA-MB-231 cells assessed by apoptosis assay using flow cytometry following exposure to 3 Gy irradiation. Cells were treated with increasing concentrations of GB (0–300 μg/mL), and viable cell populations were analyzed at 24 h (A) , 48 h (B) , and 72 h (C) hours in both non-irradiated and irradiated groups. Data are presented as mean ± SD from three independent biological experiments.

Article Snippet: The human triple-negative breast cancer (TNBC) parental cell line MDA-MB-231 (HTB-26, ATCC, Manassas, VA, USA) was cultured in DMEM supplemented with 10% heat-inactivated FBS and 1% penicillin–streptomycin.

Techniques: Apoptosis Assay, Flow Cytometry, Irradiation